Labor Analgesia
Conditions
Interventions
Control group:None
0.1 µg/ml group:dexmedetomidine 0.1ug/ml
0.2 µg/ml group:dexmedetomidine 0.2ug/ml
0.3 µg/ml group:dexmedetomidine 0.3ug/ml
0.4 µg/ml group:dexmedetomidine 0.4ug/ml
0.5 µg/ml group:dexmedetomidine 0.5ug/ml
Sponsors
Women and Children's Hospital, Qingdao University
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. 37~42 weeks gestation, singleton, nulliparous pregnant women; 2. Age 20-35 years old; 3. American Society of Anesthesiologists (ASA) grade I~II. 4. Cervical dilation 2-3cm; 5. Patients should have a detailed understanding of the nature, significance, possible benefits, possible inconveniences and potential dangers of the trial before the trial, understand the study procedures, and voluntarily sign the informed consent form in writing.
Exclusion criteria
Exclusion criteria: 1. Age under 20 or over 35, multiparous, geriatric pregnancy, multiple gestation; 2. Morbid obesity, pregnancy-related conditions (i.e., gestational diabetes, pregnancy-induced hypertension, and preeclampsia); 3. History of substance abuse, contraindications for neuraxial block; 4. Hypersensitivity to study medications; 5. Conditions increasing the risk of cesarean section (i.e., placenta previa, history of uterine abnormalities or surgical interventions), and known fetal anomalies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective analgesic;Motor block;Maternal and infant outcomes;Adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensory block; | — |
Countries
China
Contacts
Public ContactYongxin Liang
Women and Children's Hospital, Qingdao University
Outcome results
None listed