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Exploratory Study on the Clinical Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation Based on ASD Specialized Cohort

Exploratory Study on the Clinical Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation Based on ASD Specialized Cohort

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108048
Enrollment
Unknown
Registered
2025-08-22
Start date
2024-06-05
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

Test group:The patient received transcranial magnetic stimulation targeting the Cz point.
Control group:The patient received a sham stimulation targeting the Cz point.
Treatment group:The patient received transcranial magnetic stimulation targeting the DLPFC region.

Sponsors

Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria of both the "Diagnostic and Statistical Manual of Mental Disorders (5th Edition)" (DSM-5) and the ADOS-2. The diagnosis is made by the chief physician; (2) The subjects' age ranges from 2 to 7 years old; (3) The Wechsler Intelligence Scale score is greater than 70 points; (4) Right-handed; (5) The children, parents, or guardians have given consent to participate in this study.

Exclusion criteria

Exclusion criteria: (1) Having a clear history of neurological disorders, traumatic brain injury, or severe physical diseases; (2) Subjects with implanted metal devices, including non-detachable dentures; (3) Skin surface damage at the stimulation site.

Design outcomes

Primary

MeasureTime frame
Autism Behavior Rating Scale;

Secondary

MeasureTime frame
Brain functional connectivity;BDNF;

Countries

China

Contacts

Public ContactHao Yan

Tongji Medical College, Huazhong University of Science and Technology

haoyaner@163.com+86 139 7167 9960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026