gastric disease
Conditions
Interventions
Gold Standard:The development and progression of gastric cancer often involve a linear sequence from chronic inflammation to atrophy, intestinal metaplasia, low-grade intraepithelial neoplasia, high-g
Index test:Two-photon Microscopy Imaging Technology
Sponsors
The First Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Indications for gastric mucosal biopsy during gastroscopy include: (1) high suspicion of malignant tumors requiring pathological confirmation; (2) gastric ulcers; (3) polyps; (4) erosions or inflammation with an undetermined nature necessitating pathological diagnosis. 2. Eligible patients must be aged >=18 and <=80 years, regardless of gender; 3. Capable of independently completing the informed consent process.??
Exclusion criteria
Exclusion criteria: 1. vulnerable populations, minors, and pregnant women; 2. use of oral anticoagulants within the past 7 days; 3. severe coagulopathy; 4. high risk of gastrointestinal perforation (e.g., active gastrointestinal bleeding, gastrointestinal bleeding within the past 7 days, or severe gastric ulcers).?
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological Classification;Diagnostic agreement? between two pathologists;Diagnostic sensitivity between two pathologists;Diagnostic specificity between two pathologists;Measurement of Collagen Fiber Orientation Dispersion;Measurement of Collagen Area Percentage; | — |
Countries
China
Contacts
Public ContactNing Bo
Department of Gastroenterology, the First Medical Center of PLA General Hospital, Beijing 100853,China
Outcome results
None listed