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Analysis and study on the clinical efficacy of ultrasound-guided fixed-point intervention of sinomenine hydrochloride combined with radiofrequency thermocoagulation in the treatment of postpartum sacroiliac joint pain

Analysis and study on the clinical efficacy of ultrasound-guided fixed-point intervention of sinomenine hydrochloride combined with radiofrequency thermocoagulation in the treatment of postpartum sacroiliac joint pain

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108001
Enrollment
Unknown
Registered
2025-08-22
Start date
2025-08-27
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sacroiliac joint pain

Interventions

Control group:Radiofrequency thermocoagulation of the sacroiliac joint under dual guidance of ultrasound and CT
Experimental group:Ultrasound + CT dual-guided radiofrequency thermocoagulation of the sacroiliac joint combined with preoperative ultrasound-guided injection of hydrochloric ephedrine

Sponsors

Nanjing Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Sacroiliac joint pain that occurs in the parturient within two months after giving birth; 2. Age >= 18 years old; 3. For those who meet the diagnostic criteria for sacroiliac joint pain, the diagnosis is mainly based on medical history, symptoms, signs, imaging examinations and diagnostic injections, etc. Patients with positive three or more sacroiliac joint irritation tests, or those with local pain in the sacroiliac joint and positive single-finger test, who receive diagnostic injections of lidocaine and have their pain effectively reduced by more than 75%; 4. Patients who have not used other treatment methods one month before treatment and during the treatment period; 5. The subjects signed the informed consent form and voluntarily participated in this research project.

Exclusion criteria

Exclusion criteria: 1. Acute and chronic infections in other parts; 2. Other hip joint diseases; 3. Abnormalities of organs such as the heart and kidneys; 4. Have a history of asthma or be intolerant to research drugs; 5. Coagulation mechanism disorder.

Design outcomes

Primary

MeasureTime frame
NRS(Number rating scale);

Secondary

MeasureTime frame
ODI(Oswestry disability index);The Patient Health Questionnaire-9(PHQ-9);Generalized Anxiety Disorder-7(GAD-7);NLPR3;Caspase-1mRNA;IL-1ß;TNF-a;IL-6;

Countries

China

Contacts

Public ContactYue Li

Nanjing Maternal and Child Health Hospital

yuelicz@163.com+86 137 7638 8018

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026