Obesity and related metabolic diseases
Conditions
Interventions
Gastric Bypass Stent Implantation Group:None
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The following patients who are ineffective in lifestyle modification and have poor response to non-invasive treatment and drug treatment: BMI>=30.0 and two or more metabolic syndrome components, namely: (1) abdominal obesity (waist circumference >=90 cm for men, >=85 cm for women) (2) hyperglycemia (fasting blood glucose >=6.1 mmol/L or 2-hour postprandial blood glucose >=7.8 mmol/L, or diagnosed diabetes mellitus and receiving treatment) (3) hypertension (blood pressure>=130/85). mmHg or confirmed hypertension and treated) (4) fasting triglycerides (TG) >=1.70 mmol/L, or fasting high-density lipoprotein cholesterol (HDL-C) =32.5 and two or more of the following comorbidities: non-alcoholic fatty liver disease, abnormal glucose and lipid metabolism, hyperuricemia, hypertension, atherosclerosis, polycystic ovary syndrome, obstructive sleep apnea, gastroesophageal reflux, insulin resistance.
Exclusion criteria
Exclusion criteria: 1. Those who have taken antiplatelet drugs or anticoagulant drugs such as aspirin in the past month; Patients with basic loss of pancreatic islet ß cell function, C-peptide 2.5 times, total bilirubin > 35, serum creatinine concentration greater than 180 µmol/L; Definitive diagnosis of type 1 diabetes; Patients with ASA greater than or equal to grade III.; Drug or alcohol abuse addiction or suffering from uncontrollable mental illness; Duodenal bulb ulcer, gastric ulcer or previous and existing pancreatitis; Coronary heart disease, angina, cardiac function grade III or above, or pulmonary dysfunction; Patients who have undergone ERCP surgery; Patients with potential bleeding or telangiectasia in the stomach, esophagus, small intestine and other parts; Have a history of systemic lupus erythematosus, scleroderma; Those who have contraindications to endoscopy (judged by clinicians); Pregnant women or those who are preparing to become pregnant; Those who are allergic to nickel-titanium; Any other situation that the clinician deems inappropriate for participation in this product.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage reduction in BMI from baseline; | — |
Countries
China
Contacts
Public Contactfupeng
Shandong Provincial Third Hospital
Outcome results
None listed