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Fragility fractures and risk of periprosthetic fracture after joint replacement

The impact of previous fragility fractures on periprosthetic fracture after total joint arthroplasty: a retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107994
Enrollment
Unknown
Registered
2025-08-22
Start date
2025-08-25
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periprosthetic fracture

Interventions

Fragility fracture history group:None
Non-fragility fracture history group:None

Sponsors

Traditional Chinese Medicine Hospital of Ya'an
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=50years, no restriction on gender; 2. Underwent primary total knee arthroplasty (TKA) or total hip arthroplasty (THA) at our institution; 3. Complete preoperative and postoperative data available, including medical history, imaging; 4. At least 6 months of follow-up after surgery; 5. Consent for retrospective data usage was obtained or waived per IRB approval.

Exclusion criteria

Exclusion criteria: 1. Patients with periprosthetic fractures due to high-energy trauma (e.g., motor vehicle accidents); 2. Underwent revision surgery or had periprosthetic infection, tumor, severe deformity, or hardware failure; 3. Presence of severe hepatic/renal insufficiency or hematologic disorders; 4. Incomplete records or follow-up duration <6 months; 5. Refusal or inability to extract relevant clinical data.

Design outcomes

Primary

MeasureTime frame
Occurrence of periprosthetic fracture;From date of index arthroplasty to last follow-up or occurrence of PPF;

Secondary

MeasureTime frame
Osteoporosis medication usage;

Countries

China

Contacts

Public ContactHanyu Lin

Traditional Chinese Medicine Hospital of Ya'an

ddt1@qq.com+86 136 9620 6253

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026