Chronic postsurgical pain (CPSP)
Conditions
Interventions
Observation group:None
Sponsors
Yancheng First People's Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 40–59 years; 2. Scheduled to undergo elective breast cancer surgery under general anaesthesia, specifically total mastectomy with axillary lymph node dissection or modified radical mastectomy, without prior neoadjuvant chemotherapy or radiotherapy; 3. American Society of Anesthesiologists physical status I–III; 4. No history of chronic pain, including but not limited to chronic neuropathic pain or chronic musculoskeletal pain; 5. Able to complete the traditional Chinese medicine constitution assessment within 24 hours before surgery; 6. No language, hearing, or cognitive impairment that could interfere with questionnaire completion, and able to understand and complete pain assessments and related questionnaires reliably; 7. Willing to provide written informed consent and able to complete the 90-day postoperative follow-up.
Exclusion criteria
Exclusion criteria: 1. Severe psychiatric disorder, currently unstable psychiatric symptoms, cognitive impairment, or any other condition preventing reliable completion of the study questionnaires; 2. Long-term regular use of analgesics, antidepressants, psychotropic medications, or other medications considered likely to substantially interfere with pain assessment; 3. Pregnancy or breastfeeding; 4. Severe cardiac dysfunction, respiratory failure, severe hepatic dysfunction, or renal insufficiency; 5. Anticipated inability to complete the 90-day postoperative follow-up; 6. Refusal to undergo the preoperative assessment or failure to provide written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinically relevant CPSP; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total cumulative dose of all opioid and non-opioid analgesics administered within 72 hours postoperatively.;NRS pain scores at rest and during movement;Pain location and patient-reported pain characteristics; | — |
Countries
China
Contacts
Public ContactZhu Jixiang
Yancheng First People's Hospital
Outcome results
None listed