Mild Cognitive Impairment
Conditions
Interventions
Control Group:None
Sponsors
Central Hospital of Dalian University of Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Patients with cognitive impairment or normal cognitive function screened by Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA); 3. For patients diagnosed with cognitive impairment according to the Diagnostic and Statistical Manual of mental Disorders-V (DSM-V) of the United States, trace back to the first screening of mild cognitive impairment (identified by educational based MMSE and MoCA scores). From that date, the clinical and imaging data (dynamic) of more than 3 years were retrospectively collected, and the data were complete. The control group had a dynamic medical history of more than 3 years, and the clinical and imaging dynamic data were complete; 4. Life expectancy >= 3 years; 5. Informed consent of patients or family members.
Exclusion criteria
Exclusion criteria: 1.Patients with an undetermined time of diagnosis of mild cognitive impairment; 2. Cognitive dysfunction caused by special uncontrollable factors: such as brain tumor, brain injury, surgery, acute infection, poisoning, paraneoplastic syndrome, etc; 3.Severe systemic diseases; 4. Reversible cognitive dysunction caused by metabolic diseases: such as thyroid dysfunction, vitamin B12 deficiency, alcoholism, etc.; 5. Cognitive dysfunction caused by long-term use of drugs: such as sedatives, anticholinergic drugs, antiepileptic drugs, etc.; 6. Patients participated in other interventional clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of Daily Living;Anxiety and Depression;Etiological Diagnosis; | — |
Countries
China
Contacts
Public ContactJinjie Liu
Central Hospital of Dalian University of Technology
Outcome results
None listed