Obstructive sleep apnea-hypopnea syndrome High blood pressure
Conditions
Interventions
Control group:OSAHS hypertension
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. According to the 2024 Chinese Guidelines for Hypertension Prevention and Treatment, Patients with blood pressure =140/90 mmHg in the office or at home >=135/85mmHg or 24h ambulatory blood pressure >=130/80 mmHg, daytime blood pressure =135/85mmHg, and nighttime blood pressure >=120/70 MMHG without the use of antihypertensive drugs . 2. Patients aged 18-75 years; 3. Complete sleep breathing monitoring for > 5h; 4. Sign informed consent;
Exclusion criteria
Exclusion criteria: 1.Patients with secondary hypertension ; 2.Patients with type I and type II diabetes; 3.Patients with coronary angiography or coronary CTA epicardial coronary macrovascular stenosis > 50%; 4. Patients allergic to the use of pharmaceutical ingredients during transthoracic Doppler echocardiography; 5. Severe renal failure eGFR < 60ml/min/1.73m2 ; 6.Serious physical diseases, malignant tumors and mental and psychological diseases; 7.The investigator judged that the patient had poor compliance and could not complete the study as required;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distal flow reserve of anterior descending coronary artery: ratio of peak diastolic flow rate:CFVR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resistance index of microcirculation without wire based on QFR technology:AMR; | — |
Countries
China
Contacts
Public ContactMing Lou
Xuzhou Central Hospital
Outcome results
None listed