Generalized anxiety disorder
Conditions
Interventions
Healthy Control Group:None
HD-tDCS Sham Group:High-definition direct current stimulation(pseudo-stimulation mode)
HD-tDCS Active Stimulation Group:High-definition direct current stimulation
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Healthy control group : (1) Normal mental status examination; (2) Hamilton Anxiety Rating Scale (HAMA) score <=7; (3) Aged 18-65 years, matched with the anxiety disorder group in terms of age, gender, marital status, years of education, and social functioning variables; (4) Willing to participate in this study and having signed the informed consent form. 2.GAD patients: (1) Meeting the diagnostic criteria for generalized anxiety disorder (GAD) according to the International Classification of Diseases, 10th Revision (ICD-10); (2) Aged 18–65 years; (3) Hamilton Anxiety Rating Scale (HAMA) score =15; (4) Right-handed; (5) Willing to participate and having provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Healthy control group: (1) severe physical diseases; (2) mental retardation or mental retardation (IQ<90); (3) Pregnant women; (4) Previous history of mental disorders or family history of mental disorders; (5) History of psychoactive substance abuse. 2. GAD patients: (1) Patients with severe physical diseases, infectious diseases and immune system diseases; (2) Patients with severe neurological diseases, mental retardation or brain organic diseases; (3) Pregnant or lactating women; (4) Those who have received electroconvulsive therapy in the past 3 months; (5) History of seizures; (6) Metal implants in the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive Function Level;Functional Near-infrared Spectroscopy,fNIRS;Anxiety Symptom Severity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depressive Symptom Severity; | — |
Countries
China
Contacts
Public ContactYuanyuan Zhang
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed