Mild cognitive impairment
Conditions
Interventions
control group:Mental health education and promotion
Intervention Group:Computerized Cognitive Remediation Therapy (CCRT) and mental health education
Trial group:None
Sponsors
Zhongshan Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Permanent residents aged 18 and above in Zhongshan City;
Exclusion criteria
Exclusion criteria: 1. Those with schizophrenia, bipolar disorder, PTSD, or other severe mental disorders; 2. those with organic brain diseases or other severe physical illnesses; 3. those with a history of drug or alcohol abuse; 4. those with a family history of mental illness; 5. those who did not sign the informed consent form or refused follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain MRI Data;Montreal Cognitive Assessment (MoCA);Mini-Mental State Examination (MMSE);Serum BDNF;Plasma GFAP;Serum cortisol;Plasma p-Tau181;Plasma NfL;Serum CRP;Serum Aß40?Aß42; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of Daily Living Scale(ADL);Patient Health Questionnaire-9 (PHQ-9);Pittsburgh Sleep Quality Index (PSQI);genetic polymorphism loci; | — |
Countries
China
Contacts
Public ContactXinxia Liu
Zhongshan Third People's Hospital
Outcome results
None listed