Acute myocardial infarction complicated with cardiogenic shock
Conditions
Interventions
Sponsors
Huai'an First People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or female aged 18 to 80 years; 2. Acute myocardial infarction (STEMI/NSTEMI) with cardiogenic shock and ECMO support >=24 hours; 3. Receiving antiplatelet therapy: aspirin alone, 1 P2Y12 receptor antagonist: clopidogrel or ticagrelor, or dual antiplatelet therapy: aspirin 1 P2Y12 receptor antagonist: clopidogrel or ticagrelor.
Exclusion criteria
Exclusion criteria: 1.Patients were excluded if they had undergone coronary revascularization within the past 3 months or were currently taking oral anticoagulants; 2.Patients were excluded if they had received oral antiplatelet agents or intravenous glycoprotein IIb/IIIa inhibitors within 7 days of hospital admission; 3.Patients with a history of large-territory cerebral infarction or intracranial hemorrhage; 4.Patients with active bleeding or significant hemorrhagic diathesis (e.g., intracranial hemorrhage) requiring anticoagulation-free ECMO support; 5.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major bleeding events during ECMO support, defined as Bleeding Academic Research Consortium (BARC) type 3 or higher; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day all-cause mortality;Incidence of ischemic events during ECMO support;ECMO weaning success rate; | — |
Countries
China
Contacts
Public ContactHuang Ying
Huai'an First People's Hospital
Outcome results
None listed