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High-Protein Isomeric Short-Peptide Enteral Nutrition Formula for Nutritional Support Therapy in Chinese Critically Ill Patients—A Multicenter, Prospective, Real-World Observational Study

High-Protein Isomeric Short-Peptide Enteral Nutrition Formula for Nutritional Support Therapy in Chinese Critically Ill Patients—A Multicenter, Prospective, Real-World Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107956
Enrollment
Unknown
Registered
2025-08-21
Start date
2026-08-06
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are unable to eat orally and require (and can safely establish) a nasoenteral or nasogastric tube to initiate complete enteral nutrition support (artificial feeding access).

Interventions

Observation group:None

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Participants >=18 years of age; 2.= 7 days of ICU care; 4.Presence of at least one organ failure (SOFA score >= 2 points for any individual organ system); 5.Unable to tolerate oral intake, requiring and being eligible for nasoenteral or nasogastric tube placement to initiate complete enteral nutrition support via artificial feeding route; 6.Enteral nutrition therapy using a high-protein, isosmotic peptide-based formula; 7. Signed informed consent form by the person/guardian voluntarily;

Exclusion criteria

Exclusion criteria: 1.Patients receiving palliative care or those with an anticipated death within 48 hours; 2.Patients hospitalized for more than 7 days prior to this ICU admission; 3.Pregnant or lactating patients; 4.Patients previously enrolled in this study; 5.Patients assessed by the attending physician as requiring protein restriction (e.g., hepatic encephalopathy, severe renal insufficiency, etc.) or those with other conditions making them ineligible for participation in this study;

Design outcomes

Primary

MeasureTime frame
The incidence rate of gastrointestinal dysfunction;

Secondary

MeasureTime frame
Clinical Indicators;Nutritional status indicators;Laboratory test results;

Countries

China

Contacts

Public ContactQin-Dong Shi

The First Affiliated Hospital of Xi'an Jiaotong University

shiqindong@163.com+86 29 85323215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026