Patients who are unable to eat orally and require (and can safely establish) a nasoenteral or nasogastric tube to initiate complete enteral nutrition support (artificial feeding access).
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Participants >=18 years of age; 2.= 7 days of ICU care; 4.Presence of at least one organ failure (SOFA score >= 2 points for any individual organ system); 5.Unable to tolerate oral intake, requiring and being eligible for nasoenteral or nasogastric tube placement to initiate complete enteral nutrition support via artificial feeding route; 6.Enteral nutrition therapy using a high-protein, isosmotic peptide-based formula; 7. Signed informed consent form by the person/guardian voluntarily;
Exclusion criteria
Exclusion criteria: 1.Patients receiving palliative care or those with an anticipated death within 48 hours; 2.Patients hospitalized for more than 7 days prior to this ICU admission; 3.Pregnant or lactating patients; 4.Patients previously enrolled in this study; 5.Patients assessed by the attending physician as requiring protein restriction (e.g., hepatic encephalopathy, severe renal insufficiency, etc.) or those with other conditions making them ineligible for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of gastrointestinal dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Indicators;Nutritional status indicators;Laboratory test results; | — |
Countries
China
Contacts
The First Affiliated Hospital of Xi'an Jiaotong University