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Mapping microglia and astrocyte activation in Schizophrenia

Mapping microglia and astrocyte activation in Schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107941
Enrollment
Unknown
Registered
2025-08-21
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Schizophrenia group:None
Healthy control group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Schizophrenia group: (1) Age 18-40 years old, gender is not limited, right-handed; (2) According to the sixth edition of the Diagnostic and Statistical Manual of Mental Disorders, our hospital was diagnosed as a patient with schizophrenia; (3) Able to cooperate with MRI scanning; (4) Sign the informed consent form and voluntarily participate in the study. 2. Healthy control group: (1) Age 18-40 years old, gender is not limited, right-handed; (2) No history of schizophrenia and neurological diseases; (3) No abnormal findings on head MRI; (4) Able to cooperate with MRI scanning; (5) Signed informed consent and voluntarily participated in the study.

Exclusion criteria

Exclusion criteria: 1.Contraindications for MRI (such as metallic implants in the body, claustrophobia); 2.Pregnant or breastfeeding women; 3.Inability to cooperate during the MRI scan; 4.Recent history of major surgery or trauma within the past six months.

Design outcomes

Primary

MeasureTime frame
NeuroGlial Activation Dynamics Index;

Countries

China

Contacts

Public ContactSu Lui

West China Hospital of Sichuan University

2323008200@qq.com+86 18980602270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026