acute disorders of consciousness
Conditions
Interventions
tDCS combined with SPT group:tDCS combined with standardized position transformation
SPT group:standardized position transformation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for aDOC patients: 1. The GCS scale score is 4-8 points, and the GCS sports score < 5 points; 2. The duration of consciousness disorders is 14-21 days; 3. Age range from 18-65 years old; 4. Brain CT scan shows brain injury including traumatic and non traumatic with no more than 30% of the brain lobes damaged; 5. The patient's basic vital signs are stable; 6. The patient's family members sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. The patient's vital signs are unstable and the condition is worsening; 2. Patients with secondary or multiple brain injuries; 3. aDOC patients caused by hypoxic encephalopathy or other viral encephalitis; 4. Patients with severe organ disorders such as heart, liver, and kidney failure; 5. The patient is currently participating in other clinical trials that may affect the evaluation of the results of this study; 6. Individuals with metal implants or implanted pacemakers in the brain are contraindicated for tDCS treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| coma recovery scale?revised;full outline of un-responsiveness scale;Glasgow outcome scale-Extended;Incidence and severity of adverse events;electroencephalography;functional near-infrared spectroscopy;somatosensory evoked potential; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow coma scale; | — |
Countries
China
Contacts
Public ContactChengsen Jia
Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University
Outcome results
None listed