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A multicenter retrospective study for the allo-HSCT mortality risk model in children with Aplastic anemia

A multicenter retrospective study for the allo-HSCT mortality risk model in children with Aplastic anemia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107925
Enrollment
Unknown
Registered
2025-08-21
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pediatric aplastic anemia

Interventions

Training group:none

Sponsors

Wuhan Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: From January 2021 to December 2023, AA children aged 0-18 years who received allo-HSCT for the first time were followed up regularly for one year or more

Exclusion criteria

Exclusion criteria: 1. Two or more transplants; 2. Parents/guardians/patients refuse to participate; 3. Cases that are not suitable for inclusion after discussion

Design outcomes

Primary

MeasureTime frame
The time from diagnosis to transplantation;Donor type;Transplantation plan;Neutrophil levels before transplantation;Hematopoietic stem cell transplantation comorbidity index;Platelet count after transplantation;EBV/CM infection;Graft-versus-host disease;thrombotic microangiopathy;

Secondary

MeasureTime frame
ABO blood group matching;The total volume of red blood cell transfusion before transplantation;HCT-CI;

Countries

China

Contacts

Public ContactXiong Hao

Wuhan Children’s Hospital (Wuhan Medical Care Centre for Women and Children) Tongji College, Huazhong University of Science and Technology

xionghao@zgwhfe.com+86 130 0610 7360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026