Overweight and Obese
Conditions
Interventions
Placebo group:Participants will follow a calorie-restricted diet and perform resistance training four days per week, while consuming one sachet of placebo within 30 minutes prior to exercise, for a to
Protein supplement group:Participants will follow a calorie-restricted diet and perform resistance training four days per week, while consuming one sachet of protein supplements within 30 minutes prio
Functional ingredient supplement group:Participants will follow a calorie-restricted diet and perform resistance training four days per week, while consuming one sachet of active supplements within 30
Sponsors
Second Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 25–45 years, male or female; 2. Body Mass Index (BMI) between 24.0 and 29.9 kg/m^2; 3. Engaged in leisure-time physical activity but not in structured resistance training for at least 12 months; 4. Habitual protein intake < ~1.6 g/kg body weight per day; 5. Willing and able to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Current smoking, excessive alcohol use, or other unhealthy lifestyle habits (e.g., chronic sleep deprivation); 2. Use of anabolic steroids or protein-synthesis–enhancing supplements (e.g., HMB, creatine, BCAAs) within the past year; 3. Uncontrolled metabolic or cardiovascular disorders, including heart disease, hypertension, diabetes, thyroid dysfunction, or hypogonadism; 4. Clinically significant hepatic, renal, musculoskeletal, autoimmune, neurological, or psychiatric disorders; 5. Gastrointestinal diseases impairing nutrient digestion or absorption (e.g., chronic diarrhea, severe inflammation, active peptic ulcer, or history of major GI surgery); 6. Known allergy to study product ingredients or congenital metabolic disorders; 7. Pregnancy, lactation, or significant gynecological issues (e.g., severe dysmenorrhea, marked menstrual irregularity); 8. Any other condition considered by the investigators to render the participant unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;Glycated hemoglobin ;Glycated albumin;Fasting insulin;Glucagon-like peptide-1;Triglycerides ;Total cholesterol;Body weight;Body fat percentage;Lean body mass; | — |
Countries
China
Contacts
Public ContactPianhong Zhang
Department of Nutrition, Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed