Analgesic and recovery quality after cesarean section
Conditions
Interventions
Experimental group:Patient controlled intravenous analgesia (PCIA):
esketamine 1.5mg/kg+dexmedetomidine 2.0 ug/kg+tropisetron 4 mg
Control group:Patient controlled intravenous analgesia (PCIA):
butorphanol 0.15mg/kg+dexmedetomidine 2.0 ug/kg+tropisetron 4 mg
Sponsors
The Second Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Pregnant women who undergo cesarean section under combined spinal and epidural anesthesia at 37-42 weeks of gestation; 2. Age range: 20-45 years old; Body Mass Index (BMI) 18-35 kg/m ²; 3. ASA classification level II; 4. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Contraindications for intrathecal anesthesia and mental disorders; 2. Serious obstetric complications or potential medical conditions; 3. Allergies or contraindications to any medication used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| PCIA press frequency;Edinburgh Postnatal Depression Scale (EPDS) score;Incidence of postoperative adverse events;Assessment of Nighttime Sleep in the First Two Nights After Surgery; | — |
Countries
China
Contacts
Public ContactZhiqiang Lu
The Second Affiliated Hospital of Nanjing Medical University
Outcome results
None listed