Application of amino acid peritoneal dialysis solution in malnourished peritoneal dialysis patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500107912

Enrollment

Unknown

Registered

2025-08-20

Start date

2024-04-26

Completion date

Unknown

Last updated

2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease

Interventions

Test group:Malnourished PD patients use one bag of amino acid peritoneal dialysis solution per day

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The serum albumin level before using amino acid peritoneal dialysis solution was 25-38g/L; 2. 18 to 75 years old, regardless of gender; 3. Stable peritoneal dialysis treatment for PD patients for more than 3 months; 4. Weekly total Kt/V>1.7; 5. Blood potassium>3.5mmol/L; 6. C-reactive protein or high-sensitivity C-reactive protein<2 x upper limit of normal value; 7. The binding capacity of carbon dioxide is greater than 22mmol/L.

Exclusion criteria

Exclusion criteria: 1. If peritonitis, other infections, or inflammatory diseases occur within the first 3 months before the screening period; 2. Contraindications for amino acid peritoneal dialysis fluid; 3. The blood sugar of diabetes subjects was poorly controlled, such as HbAlc>7%; 4. Received a kidney transplant during the study period.

Design outcomes

Primary

Measure	Time frame
serum albuminserum albumin;	—

Secondary

Measure	Time frame
Blood routine;blood biochemistry;electrolyte;bicarbonate;urine output;	—

Countries

China

Contacts

Public ContactZhong Hui

West China Hospital, Sichuan University

zhonghui39@126.com+86 189 8060 0000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026