Feeding intolerance (FI)
Conditions
Interventions
Intervention group:Colostrum enema
Control group:Glycerin enema with normal saline (1:1 dilution)
Sponsors
Gansu Provincial Maternity and Child Health Care Hospital
Eligibility
Sex/Gender
All
Age
28 Years to 32 Years
Inclusion criteria
Inclusion criteria: (1) Gestational age (GA) at birth >= 28 weeks and <32 weeks. (2) Admitted to the NICU within 24 hours after birth. (3) Mother is able to provide colostrum. (4) Legal guardian provides informed consent and voluntarily agrees to participate in the study. (5) Subjects whose guardians have signed and confirmed the informed consent form, voluntarily opting to donate breast milk for intestinal infusion therapy.
Exclusion criteria
Exclusion criteria: (1) Presence of congenital anomalies (e.g., congenital heart disease, congenital gastrointestinal malformations). (2) Diagnosis of severe gastrointestinal disorders (e.g., intussusception, necrotizing enterocolitis). (3) Occurrence of severe infections or life-threatening complications (e.g., sepsis, coagulopathy). (4) Maternal contraindications to breastfeeding (e.g., HIV, syphilis, hepatitis B infection).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of feeding intolerance (FI); | — |
Countries
China
Contacts
Public ContactShixiang Hou
Gansu Provincial Maternity and Child Health Care Hospital
Outcome results
None listed