Chronic wounds
Conditions
Interventions
Control group:None
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.>=18 years old; 2. Chronic wounds caused by various causes (lasting more than 30 days without healing), including stage 3-4 pressure injuries (PI), non-healing surgical incisions, traumatic wounds, vascular ulcers, etc.; 3. There are indications for negative pressure wound treatment, such as wound area of more than 8cm^2 and/or depth of more than 2cm, 24-hour exudate volume of more than 10ml, poor drainage, etc.
Exclusion criteria
Exclusion criteria: 1. Malignant wound or with necrotic tissue (yellow or black wound base) but contraindicated to debridement or unable to be debrided; 2. Systemic infection requiring antibiotics or with untreated osteomyelitis; 3. Combined with bleeding tendency, coagulation dysfunction, or wound with exposed nerves, blood vessels or active bleeding; 4. Systemic comorbidities that affect wound healing, such as severe malnutrition, autoimmune diseases, etc.; 5. Use steroid hormones, immunosuppressants, chemotherapy drugs and other drugs that affect wound healing; 6. The wound cannot form a closed environment; 7. Consciousness disorder or inability to actively cooperate with treatment; 8. Patients with missing retrospective case data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of dressing changes and duration of negative pressure wound therapy;Bates-Jensen Wound Assessment Tool (BWAT) scores;Visual Analogue Scale (VAS) scores ;Anxiety scores ;Depression scores ;Bacterial culture results;Length and cost of hospitalization;Adverse outcomes such as patient death, amputation, and implant failure; | — |
Countries
China
Contacts
Public ContactXiang Huang
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed