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The Impact of Chewing Gum on Intestinal Activity in Patients After Esophageal Cancer Radical Surgery: A Randomized Controlled Study

The Impact of Chewing Gum on Intestinal Activity in Patients After Esophageal Cancer Radical Surgery: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107896
Enrollment
Unknown
Registered
2025-08-20
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Control group:The control group received the conventional perioperative treatment and rehabilitation nursing methods for esophageal cancer: Preoperatively: All patients were given a clear liquid diet
if well-tolerated, other liquids were provided until the first flatus. After the first flatus, a semi-liquid diet was started. Patients continued on a semi-liquid diet until de

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who underwent esophagectomy and gastric pull-up for the treatment of esophageal malignant tumors; patients aged between 18 and 80 years.

Exclusion criteria

Exclusion criteria: Patients with loose teeth, chronic constipation, inflammatory bowel disease, or a history of previous intestinal surgery or neoadjuvant chemotherapy; patients with an operation time exceeding 5 hours or an intensive care unit (ICU) stay exceeding 24 hours after surgery. The surgery and ICU time limits included in this study are set at 5 hours and 24 hours, respectively. This is because the research team, after a retrospective review of all patients who underwent esophagectomy in the hospital, found that most patients with an operation time exceeding 5 hours or an ICU stay exceeding 24 hours had severe intraoperative or postoperative complications.

Design outcomes

Primary

MeasureTime frame
Time to first flatus and time to first defecation after surgery;

Secondary

MeasureTime frame
Additional analgesic requirements;Incidence rate of postoperative intestinal obstruction;Incidence rate of anastomotic leakage;Length of hospital stay;

Countries

China

Contacts

Public ContactJIan Zhang

The Third Affiliated Hospital of Sun Yat-sen University

Sumszhangjian@163.com+86 139 2219 2727

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026