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A comparative study of different target repetitive transcranial magnetic stimulation on language rehabilitation in patients with aphasia after stroke

A comparative study of different target repetitive transcranial magnetic stimulation on language rehabilitation in patients with aphasia after stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107839
Enrollment
Unknown
Registered
2025-08-19
Start date
2023-07-17
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke aphasia

Interventions

Group A:The left DLPFC area was stimulated first (the stimulation coil plane was tangential to the stimulation target, the treatment intensity was 90% of the healthy limb motor evoked potential thresh
Group B:The left DLPFC area was stimulated first (the stimulation parameters were the same as those of the left DLPFC area true stimulation-right Broca area true stimulation group), and then the right

Sponsors

Department of Rehabilitation, Second Affiliated Hospital of Air Force Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : ( 1 ) According to the diagnostic criteria of stroke, the first onset of stroke was confirmed by CT or MRI, and the lesion was limited to the left cerebral hemisphere ; ( 2 ) Non-fluent aphasia was diagnosed by Western Aphasia Examination ( WAB ). ( 3 ) The course of disease was 1 week to 6 months, male and female, aged 30-80 years old ; ( 4 ) Conscious when entering the group, stable vital signs, able to carry out and complete basic treatment ; ( 5 ) All were right-handed ; ( 6 ) Before the onset of speech function is normal, mother tongue is Chinese ; ( 7 ) Willingness to actively recover and can cooperate with treatment instructions ; ( 8 ) Patients and / or authorized patients ' families to understand and sign the informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria : ( 1 ) patients with severe cognitive impairment or mental illness who cannot cooperate with treatment and evaluation ; ( 2 ) with severe dysarthria ; ( 3 ) Patients with intracranial metal foreign bodies ; ( 4 ) Patients with a history of epilepsy or family history of epilepsy ; ( 5 ) Patients with cardiac pacemakers, stents and cochlear implants ; ( 6 ) Cerebral hemorrhage or subarachnoid hemorrhage not absorbed.

Design outcomes

Primary

MeasureTime frame
Western Aphasia Battery ( WAB );

Secondary

MeasureTime frame
Boston Aphasia Diagnostic Test(BDAE);activity of daily living scale(ADL);Montreal Cognitive Assessment ( MoCA );

Countries

China

Contacts

Public ContactLiu Rui

Department of Rehabilitation, Second Affiliated Hospital of Air Force Military Medical University

speciallr@163.com+86 150 0299 5399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026