Diseases of the biliary tract and pancreas
Conditions
Interventions
Experimental Group:Low-dose esketamine combined with cyclopofol group
Control group:Sufentanil combined with propofol group
Sponsors
Quzhou People Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 65 and 80; 2.) The anesthesia risk classification of the American Academy of Anesthesiologists (ASA) is grade II to III; 3. Body mass index (BMI) : 18 to 30 kg/m^2; 4. To undergo endoscopic retrograde cholangiopancreatography (ERCP) at an elective date; 5. Be able to understand the research content and voluntarily sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to the test drugs (esketamine, cyclopofol, sufentanil or propofol); 2. Has a history of severe hypertension, intracranial hypertension, uncontrolled hyperthyroidism, or glaucoma; 3. Those who have had respiratory tract infections or significantly impaired lung function recently; 4. Has a history of severe craniocerebral trauma or cerebrovascular accident in the past; 5. Those with mental disorders or who have been taking antipsychotic drugs for a long time; 6. Those with severe liver or kidney dysfunction, ascites or renal failure; 7. Patients with severe sleep apnea syndrome; 8. Failing to sign the informed consent form or refusing to participate in this researcher;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During the operation, vital signs (HR, MAP, SPO?) indicators at key time points were continuously recorded; | — |
Countries
China
Contacts
Public ContactShufen Yang
Quzhou People Hospital
Outcome results
None listed