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A prospective multicenter real-world clinical study plan for the standardized management of anti-tumor treatment-related nausea and vomiting (CINV) in China

A prospective multicenter real-world clinical study plan for the standardized management of anti-tumor treatment-related nausea and vomiting (CINV) in China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107825
Enrollment
Unknown
Registered
2025-08-19
Start date
2025-08-19
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumor

Interventions

Research Group:Not involved

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with malignant tumors confirmed by pathology; (2) Plan to receive at least one complete cycle of anti-tumor treatment regimens with moderate to high emetic risk (HEC/MEC) (including anti-tumor treatments with emetic risk such as chemotherapy, ADC therapy, TKIs, radiotherapy, CAR-T, etc., as well as their combination treatments); (3) Normal cognitive ability, capable of completing the patient diary records and scales required by the research (4) Sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Currently undergoing or about to receive treatment that may cause nausea and vomiting (except for anti-tumor treatment); (2) Combined with uncontrolled stable intracranial metastases; (3) Nausea/vomiting of any cause occurred within three days before enrollment; (4) Concurrent diseases that may cause nausea and vomiting; (5) There are obvious mental disorders, and the researcher determines that the study cannot be completed; Currently participating in other clinical trials; (6) Any situation where compliance is poor or the researcher determines that the study cannot be completed.

Design outcomes

Primary

MeasureTime frame
The incidence of CINV throughout the entire cycle;Compliance rate of CINV prevention program guidelines;

Secondary

MeasureTime frame
The incidence of nausea symptoms throughout the entire cycle;There were no CINV days throughout the entire cycle;Quality of life assessment;

Countries

China

Contacts

Public ContactZhu Jiang

West China Hospital, Sichuan University

zhujiang@wchscu.cn+86 189 8060 2256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026