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Comparison of the Effects of Remimazolam and Ciprofol on Hemodynamics During Tracheal Intubation in General Anesthesia Induction

Comparison of the Effects of Remimazolam and Ciprofol on Hemodynamics During Tracheal Intubation in General Anesthesia Induction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107823
Enrollment
Unknown
Registered
2025-08-19
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Requiring Tracheal Intubation Under General Anesthesia

Interventions

Remimazolam group:Use of Remimazolam for Anesthesia Induction

Sponsors

Beijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective surgery under general anesthesia, regardless of gender, aged 18-65 years; 2. Body mass index (BMI) 19-28 kg/m²; 3. ASA physical status classification I-III; 4. All participants provided written informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. Acute heart failure, unstable angina pectoris, or myocardial infarction within the past 6 months; 2. Baseline measurements upon admission: systolic blood pressure >160 mmHg or diastolic blood pressure >100 mmHg; 3. Acute respiratory infection, acute exacerbation of COPD, or poorly controlled asthma; 4. End-stage renal failure or hepatic decompensation; 5. Psychiatric disorders including: schizophrenia, depression, cognitive dysfunction, etc. 6. Known allergy to the study medications; 7. History of benzodiazepine use within the last 3 months; 8. Pregnant or lactating women; 9. Anticipated difficult airway.

Design outcomes

Primary

MeasureTime frame
Hemodynamic Fluctuations During Anesthesia Induction;

Secondary

MeasureTime frame
Adverse Events;Other Hemodynamic Parameters;

Countries

China

Contacts

Public ContactLi Zhao

Beijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital

2493268244@qq.com+86 15228152382

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026