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A prospective, open-label, randomized controlled trial on different catheter locking frequencies in patients with dialysis catheters not removed after CRRT treatment in the Intensive Care Unit.

A prospective, open-label, randomized controlled trial on different catheter locking frequencies in patients with dialysis catheters not removed after CRRT treatment in the Intensive Care Unit.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107820
Enrollment
Unknown
Registered
2025-08-19
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control group:Lock the catheter every 24 hours.
Intervention group:Lock the catheter every 72 hours.

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have undergone CRRT treatment in the ICU and whose dialysis catheters have not yet been removed; 2. Age >=18 years, gender unrestricted; 3. The expected catheter indwelling time is >=72 hours; 4. The patient or their family members have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who have already experienced catheter dysfunction or infection before enrollment; 2. Patients who actually remove the temporary catheter during the trial period after enrollment; 3. Patients who have participated in other intervention studies within 2 months.

Design outcomes

Primary

MeasureTime frame
Survival time of the catheter;The incidence of catheter dysfunction;Incidence of bleeding events;The incidence rate of catheter-related bloodstream infection;

Secondary

MeasureTime frame
Length of stay in the ICU;Total hospital stayTotal hospital stay;Medical expenses;The number of times for performing CRRT again;The incidence rate of adverse events related to the catheter;Incidence of intraductal thrombosis;Reason for catheter removal;

Countries

China

Contacts

Public ContactLi Zhaoyang

Zhongnan Hospital of Wuhan University

lizhaoyang@whu.edu.cn+86 136 3860 6202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026