liver malignant tumors
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) unresectable primary or metastatic liver malignancy; (2) age >=18 years old; (3) ECOG =90g/L, absolute neutrophil count >1500/mm^3, platelet count >=80×10^9/L, ALT and AST<5 times the upper limit of normal value (ULN), total bilirubin <3×ULN, serum creatinine <1.5×ULN; Prothrombin time (PT) or international normalized ratio (INR), activated partial thromboplastin time (APTT) <1.5×ULN; (6) suitable for selective arterial cannulation and angiography.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Severe liver dysfunction, including severe jaundice, hepatic encephalopathy, refractory ascites or hepatorenal syndrome; (2) Child-Pugh grade C; (3) uncorrectable coagulation dysfunction; (4) renal dysfunction, liver creatinine >176.8u mol/L or creatinine clearance <30ml/min; (5) complicated with active hepatitis or infection; (6) diffuse or extensive distant metastasis; (7) abnormal vascular anatomy of the hepatic artery, or severe and uncorrectable hepatic artery-portal vein fistula or hepatic artery-hepatic vein shunt; (8) Portal vein tumor thrombus, embolism, less collateral vessel formation, and portal vein stent can not be used to recanalize the main portal vein to restore hepatic blood flow; (9) uncorrectable hepatic artery-gastrointestinal artery shunt; (10) severe contrast allergy; (11) the single lung absorbed dose exceeded 30Gy or the cumulative lung absorbed dose exceeded 50gy; (12) others: including pregnant women or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SUVmean;SULmax;SULmean;Sensitivity;Specificity; | — |
Countries
China
Contacts
The First Affiliated Hospital of Jinan University