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Research on Constructing a Precise Diagnosis Model for Peripheral Lung Lesions Based on Improved Ultrasound Contrast Imaging and Multimodal Imaging Combined with Clinical Features

Research on Constructing a Precise Diagnosis Model for Peripheral Lung Lesions Based on Improved Ultrasound Contrast Imaging and Multimodal Imaging Combined with Clinical Features

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107816
Enrollment
Unknown
Registered
2025-08-19
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral lung lesions that can be visualized using routine ultrasound

Interventions

Gold Standard:Using needle biopsy or postoperative pathology results as the gold standard
Index test:Enhancement time difference between the left ventricle and the lesion in the improved pulmonary ultrasound perfusion method

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age (18-85 years old); 2. Chest CT shows a mass around the lungs without central lung lesions; 3. Transthoracic ultrasound can clearly show the lesion; 4. Have a clear pathological diagnosis, including puncture pathology or surgical pathology; 5. Voluntary enrollment with good compliance.

Exclusion criteria

Exclusion criteria: 1. Suffer from severe heart, lung and other organ diseases; 2. Pulmonary hypertension, heart failure, unstable angina, acute or recent myocardial infarction, or adult respiratory distress syndrome; 3. Allergy or hypersensitivity to ultrasound contrast agents; 4. Lactating or pregnant women.

Design outcomes

Primary

MeasureTime frame
The time at which the left ventricle and the lesion start to enhance;

Secondary

MeasureTime frame
CT indicators (lesion morphology, presence of metastatic signs);Ultrasound contrast-enhanced imaging indicators (qualitative indicators include enhancement direction, enhancement range, enhancement boundary, and perfusion defects);Routine ultrasound indicators (size of the lesion; angle between the lesion edge and the thoracic wall: obtuse or acute; internal echo of the lesion: uniform or uneven; whether there is a hypoechoic a;

Countries

China

Contacts

Public ContactZhong Jieyu

Peking University Shenzhen Hospital

zhongjieyu0717@163.com+86 755 83923333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026