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The therapeutic effect of i-PRF on androgenic alopecia and the expression of ß-Catenin, CD34 and Ki67 in scalp tissue

The therapeutic effect of i-PRF on androgenic alopecia and the expression of ß-Catenin, CD34 and Ki67 in scalp tissue

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107781
Enrollment
Unknown
Registered
2025-08-18
Start date
2025-08-18
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male androgenic alopecia

Interventions

Traditional treatment group:oral finasteride tablets, coated with minoxidil foam
PRP combined treatment group:PRP treatment, oral finasteride tablets, coated with minoxidil foam
PRP injection group:PRP therapy
i-PRF combined treatment group:i-PRF treatment, oral finasteride tablets, coated with minoxidil foam
i-PRF injection group:IPRF treatment

Sponsors

The Second Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for AGA in Chinese Clinical Dermatology; 2. Male 18~45 years old; 3. Adopt basic and specific type (BASP) grading method, which meets the light and moderate AGA; 4. No treatment has been taken in the past 3 months.

Exclusion criteria

Exclusion criteria: 1.Hair follicles have atrophied under trichoscopy; 2.Have other skin conditions; 3.People allergic to minoxidil; 4.Long-term oral antiplatelet drugs or ongoing anticoagulation-related therapy; 5.Other systemic or mental diseases or infectious diseases; 6.Patients with a history of PRF/PRP/ micronedle /CO2 dot matrix laser/low energy laser/finasteride tablet/minoxidil use within 3 months before the first visit, or who have used drugs related to hair loss but are not clear; 7.Preparing for pregnancy.

Design outcomes

Primary

MeasureTime frame
BASP (AGA) typing;DLQI score;Trichoscopes detect the number of follicle units, average hair diameter, vellus hair ratio, and telogen hair ratio;ß-Catenin and CD34 expression and Ki67 index in scalp tissue;

Countries

China

Contacts

Public ContactLulu Tang

The Second Affiliated Hospital of Guangxi Medical University

tanglulu1@yeah.net+86 771 3394217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026