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The Influence of Dural Puncture Epidural (DPE) Technique on the Optimal Time Interval of Programmed Labor Analgesia: A Randomized Double-Blind Study

The Influence of Dural Puncture Epidural (DPE) Technique on the Optimal Time Interval of Programmed Labor Analgesia: A Randomized Double-Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107779
Enrollment
Unknown
Registered
2025-08-18
Start date
2025-09-03
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain

Interventions

Group C:The standard epidural group directly inserted an epidural catheter after confirming the epidural space. After negative negative suction of blood and CSF, 3 mL of 1.5% lidocaine and 15 µg of ep
Group DPE:Intraspinal labor analgesia was initiated. The patient was in the left lateral position, and the L3-4 intervertebral space was confirmed by ultrasound assessment. The epidural space was dete

Sponsors

The Affiliated Women's and Children's Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: ASAII, a parturient who requires labor analgesia. We included adult parturients (aged 18-45 years) who had a single pregnancy at 37-42 weeks of geterage, presented with procephaly, required intramuscular labor analgesia, had a cervical dilation of 2-5 cm, experienced regular uterine contractions every 3-5 minutes, and had a pain score (0-10, where 0 indicates no pain and 10 indicates the most severe pain) >= 4, with no obvious abnormalities.

Exclusion criteria

Exclusion criteria: 1: Refuse or contraindicate the use of intraspinal analgesia and body mass index (BMI). 35 kg/m^2, pregnance-related diseases (gestational hypertension, preeclampsia and gestational diabetes), allergy to ropivacaine or sufentanil, use of opioids or sedatives within 4 hours before requiring intraspinal analgesia, previous cesarean section, known fetal malformations and the mother's refusal to participate. Exclusion criteria: The patient was converted to cesarean section, with accidental dural perforation. The initial dose failed to achieve effective analgesia within 20 minutes (VAS <= 10 mm), and the time from the administration of a compound dose to full dilation of the cervix was less than 1 hour.

Design outcomes

Primary

MeasureTime frame
The primary assessment outcome was effective or ineffective labor analgesia.;

Secondary

MeasureTime frame
Onset of analgesia;Sensory block height;Motor block;The time from the start of labor analgesia to the total dilation of the cervix;Duration of first labor stage;Duration of second labor stage;Operative vaginal delivery;Total ropivacaine consumption ml;PCEA or manual top-ups;hypotension;Newborn birth weight;Neonatal Apgar score;Patient satisfaction;Nausea and vomiting;Itching;Headache after dural puncture;

Countries

China

Contacts

Public ContactZhongsai Yang

The Affiliated Women's and Children's Hospital of Ningbo University

yangzhongsai@126.com+86 159 6890 2962

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026