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Effects of the Endometrial Microbiota on Endometrial Carcinogenesis and DNA Methylation

Effects of the Endometrial Microbiota on Endometrial Carcinogenesis and DNA Methylation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107778
Enrollment
Unknown
Registered
2025-08-18
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial cancer

Interventions

Endometiral cancer group:None
Atypical endometrial hyperplasia group:None
Endometrial hyperplasia group:None
Control group:None

Sponsors

Shenzhen Maternity and Child Healthcare Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Case Group: 1. Age >=18 years; 2. Histopathologically confirmed diagnosis of: Endometrial hyperplasia without atypia, atypical endometrial hyperplasia, or endometrial carcer. Control Group: Patients without histopathologically confirmed endometrial hyperplasia without atypia, atypical endometrial hyperplasia, or endometrial carcer.

Exclusion criteria

Exclusion criteria: Patients who received chemotherapy, radiation therapy, or antibiotic administration within 14 days prior to enrollment.

Design outcomes

Secondary

MeasureTime frame
The Association between the Endometrial Microenvironment and Endometrial Carcinogenesis;The Impact of the Endometrial Microbiota on DNA Methylation during Endometrial Carcinogenesis;—

Primary

MeasureTime frame
Endometrial Microbiota;DNA Methylation;—

Countries

China

Contacts

Public ContactWeiwei Zeng

Shenzhen Maternity and Child Healthcare Hospital

zwwvivian@sohu.com+86 150 1383 0120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026