Coronary microvascular disease (CMVD)
Conditions
Interventions
Observation group:Administer conventional antiplatelet therapy to stabilize plaques and specifically improve coronary microcirculation
Control group:Conventional anti-platelet therapy for plaque stabilization
Sponsors
Yanqing Hospital, Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Select inpatients in the cardiology department of Yanqing District Hospital from January 2024 to June 2025 2. According to subjective symptoms and objective records of myocardial ischemia, based on CAG examination and IMR testing, CMVD patients are considered 3. Age between 40-75, male or female not limited; 4. The subjects are informed and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who have undergone revascularization within one month prior to enrollment or require revascularization after this coronary angiography. 2. Suffering from obvious liver and kidney diseases, or with alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels 1.5 times higher than the upper limit of normal, creatinine>2.0mg/dl (176.8umol/L), or glomerular filtration rate<50%; 3. Suffering from serious cardiovascular diseases such as heart failure, myocardial disease, structural heart disease, and uncontrolled hypertension; 4. Patients with serious mental illnesses, hematopoietic system disorders, malignant tumors, and other major illnesses; 5. Individuals who have participated or are currently participating in other clinical studies within the past three months; 6. For individuals suspected or clearly allergic to research drugs. 7. The research physician believes that there are other situations that are not suitable for participating in this trial, including but not limited to: subjects being unable to follow the research protocol, and potential safety hazards to the subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seattle Angina;Fractional flow reserve of coronary artery;Coronary flow reserve;Quantitative Fractional Flow Reserve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Static electrocardiogram indicators;Cardiac load; | — |
Countries
China
Contacts
Public ContactLiu Dongting
Yanqing Hospital, Peking University Third Hospital
Outcome results
None listed