Cardiovascular disease
Conditions
Interventions
Bupivacaine liposome group:At the end of the patients surgery, bupivacaine liposome injection was used for nerve block (including thoracic rectus muscle nerve block, erector spinae plane block or ante
Normal saline group:At the end of surgery, patients were treated with normal saline injection for nerve blocks (including transverse pectoralis nerve block, erector spinae plane block, or serratus ant
Sponsors
Fuwai Huaxin Cardiovascular Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Before the trial, thoroughly understand the nature, significance and potential benefits of the trial, be able to comprehend the procedures and methods of this research, be willing to strictly follow the clinical trial protocol to complete this trial, and voluntarily sign the informed consent form; 2.Schedule a minimally invasive cardiac surgery; 3. Age >= 18 years old;
Exclusion criteria
Exclusion criteria: 1. Patients with combined psychiatric disorders and cognitive dysfunction; 2. Patients with sensory disorders such as hyperalgesia, or other somatic pain that affects postoperative pain assessment; 3. Patients with a history of myocardial infarction or unstable angina within the past six months, or a history of severe arrhythmia (such as second-degree and above atrioventricular block); 4. Patients with diabetic peripheral neuropathy; 5. Patients known to be allergic to bupivacaine or other amide-type local anesthetics; 6. Pregnant or lactating patients, as well as female patients who have a fertility plan within the past six months and are unwilling or unable to take effective contraceptive measures; 7. Patients considered by the researchers to have any other factors that make them unsuitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The NRS score in the resting state at 24 hours (+/-1 hour) after the surgery.; | — |
Countries
China
Contacts
Public ContactLin Hongqi
Fuwai Huaxin Cardiovascular Hospital
Outcome results
None listed