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Effects of Intraoperative and Emergence-Phase Auditory Stimulation on Postoperative Recovery Quality and EEG Activity: A Randomized Controlled Trial

Effects of Intraoperative and Emergence-Phase Auditory Stimulation on Postoperative Recovery Quality and EEG Activity: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107736
Enrollment
Unknown
Registered
2025-08-18
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatectomy patients

Interventions

Music Group:Play soft classical music
Noise Group:Play rhythmic heartbeat noise
Soundproof Group:Use noise-canceling earplugs for environmental noise isolation
Control Group:No intervention, completely routine.

Sponsors

Huashan Hospital, Fudan University, Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Surgical procedures occurring between July 2025 and December 2025 2. Aged 18 years or older 3. Scheduled for elective operations under general anesthesia 4. Requiring hepatic surgery within general surgery department 5. ASA classification I through III 6. Having full civil capacity, voluntarily participating, and being able to understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Hearing impairment: Any degree of hearing loss or history of ear diseases. 2. History of mental illness: Diagnosis of psychiatric disorders such as schizophrenia, major depressive disorder, or bipolar disorder. 3. Neurological disorders: Suffering from epilepsy, Parkinson's disease, Alzheimer's disease, or other neurological conditions. 4. Medication use: Long-term use of sedatives, analgesics, or psychotropic drugs. 5. ASA classification IV or higher. 6. Special surgeries: History of cranial surgery, ear surgery, or other procedures that may affect hearing or EEG monitoring. 7. Pregnancy status: Pregnant or lactating women. 8. Chronic pain: History of chronic pain that may interfere with pain assessment accuracy. 9. History of alcohol or substance abuse. 10. Participation in other clinical trials: Concurrent involvement in other trials that may influence the results of this study. 11. Language barriers: Inability to communicate effectively or complete questionnaires. 12. Refusal to participate: Patient or family members decline to join the study.

Design outcomes

Primary

MeasureTime frame
Emergence agitation ;

Secondary

MeasureTime frame
Anxiety and depression;Emergence time;Cognitive function; Pain intensity;Recovery quality;Electroencephalogram Monitoring;

Countries

China

Contacts

Public ContactHonglan Sheng

Huashan Hospital, Fudan University, Shanghai

524239655@qq.com+86 138 1887 4166

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026