Diabetes
Conditions
Interventions
Metformin observation group:None
Empagliflozin observation group:None
5: 2MR observation group:None
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who participated in the EARLY study and completed the 16-week intensive intervention; 2. Be able to get in touch; 3. Volunteer to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Subjects who withdrew or lost to follow-up in the original study; 2. Received bariatric surgery or GLP-1 receptor agonists and other treatments that significantly interfere with body weight after the original study intervention; 3. Those who are currently complicated with serious diseases (such as malignant tumors, end-stage renal disease) or unable to cooperate with follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration for which HbA1c remained below 6.5%.;The proportion of subjects who maintained an HbA1c level of 6.5% or less with lifestyle intervention alone.;The duration for which HbA1c remained below 7%.;The proportion of subjects who maintained an HbA1c level of 7% or less with lifestyle intervention alone.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of coronary heart disease;Incidence of hypertension;Diabetes remission rate;Continuity and adjustment of treatment plan;Proportion of subjects with normal insulin resistance index;Proportion of subjects with normal fasting insulin;Proportion of subjects with normal glycated hemoglobin;Proportion of subjects with normal blood biochemical indicators (fasting blood glucose, blood lipids, blood uric acid).;Proportion of subjects with normal waist-to-hip ratio;Proportion of subjects with normal waist circumference;Proportion of subjects with normal body mass index (BMI).;Proportion of subjects whose body weight regain rate is less than 10% of their original body weight; | — |
Countries
China
Contacts
Public ContactGuo Lixin
Beijing hospital
Outcome results
None listed