acute respiratory distress syndrome
Conditions
Interventions
90-degree high lateral position group:Place the patient in the 90-degree high lateral position.
30-degree low lateral position group:Place the patient in the 30-degree low lateral position.
Prone position group:Patients will be placed in the prone position, i.e., lying face down.
120-degree high lateral position group:Place the patient in the 120-degree high lateral position.
Sponsors
The Fourth Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. Diagnosis of ARDS according to the Berlin Definition (2023 update). 3. Clinically evaluated as suitable for positional therapy by physicians. 4. Signed informed consent obtained from the patient or legal representative. 5. Absence of severe spinal deformities or musculoskeletal disorders that may compromise safe high lateral positioning. 6. No severe skin conditions (e.g., extensive open wounds or pressure ulcers) that may affect the feasibility of lateral positioning.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women. 2. Severe cardiac diseases (e.g., unstable arrhythmia or heart failure) that may worsen with positional changes. 3. Severe coagulation disorders with increased bleeding risk. 4. Known allergy to the EIT device or any of its components. 5. Severe psychiatric disorders impairing study compliance. 6. Current participation in experimental therapies that may affect pulmonary function. 7. Severe active infections requiring special isolation measures. 8. Anticipated need for emergency surgery or life-threatening complications within 24 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A/P Ratio;Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilation-Perfusion Ratio;Global Inhomogeneity Index, GI; | — |
Countries
China
Contacts
Public ContactSong Lijun
The Fourth Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed