Respiratory depression caused by sedative drugs
Conditions
Interventions
Group C: Jet oxygenation and ventilation through bite block group:N/A
Group B: Oxygen inhalation through bite block group:N/A
Group A: Oxygen inhalation through nasal cannula group:N/A
Group D: Jet oxygenation and ventilation+oxygen inhalation through bite block group:N/A
Sponsors
The Fourth Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. gastrointestinal endoscopy with sedation; 2. Age 18-75 years old; 3. American anesthesiologist classification I-II; 4. BMI:18-28kg/m^2; 5. The estimated duration of the surgery is less than 1 hour.
Exclusion criteria
Exclusion criteria: 1. Lesions or injuries in the oral and pharyngeal cavities; 2. Severe pulmonary disease, poor lung compliance, asthma, or severe tracheal stenosis; 3. Respiratory tract obstruction; 4. Patients who are at risk of severe bleeding during surgery and who are prone to reflux and aspiration; 5. Other contraindications for jet ventilation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of hypoxemia of different degrees in the study participants (mild: 90%-95%, moderate: 89%-80%, severe: = 79%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilation related adverse events,Circulation related adverse events,Endoscopists' satisfaction with the anesthesia process and research participants' satisfaction;Endoscopists' satisfaction with the anesthesia process and research participants' satisfaction; | — |
Countries
China
Contacts
Public ContactXuesong Ma
The Fourth Affiliated Hospital of Harbin Medical University
Outcome results
None listed