lung cancer
Conditions
Interventions
Intervention group:Microwave ablation therapy
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Definitive diagnosis of pulmonary nodule(s) by chest CT, with nodule size ranging from 1.5 to 3 cm; 2. Patient intolerance to conventional surgical treatment due to advanced age, poor cardiopulmonary function, multiple nodules, and other factors; 3. Pathological examination confirming a definitive diagnosis of lung adenocarcinoma.
Exclusion criteria
Exclusion criteria: 1. Tumor adjacent to the pulmonary hilum or major blood vessels; 2. Presence of malignant pleural effusion or metastasis to other sites; 3. Lesion size >3 cm or <1.5 cm; 4. Contraindications to microwave ablation; 5. History of immune-mediated diseases; 6. Postoperative pathological diagnosis confirming benign lesions or non-adenocarcinoma malignancies; 7. Concurrent tumors at other sites or history of radiotherapy/chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of immune cells;Number of Cytokines (IL-1ßIL-2IL-2RIL-4IL-5IL-6IL-8IL-10IL-12p70IL-17IL-18IFN-?IFN-aTNF-a);Number of Cytokines(B cell);Number of Cytokines(NK cell); | — |
Countries
China
Contacts
Public ContactLi Linjun
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed