Tardive Dyskinesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Previous mental illness; 2. Taking antipsychotic drugs; 3. Meet the diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-V) "tardive dyskinesia" diagnostic criteria; 4. Aged between 18 and 60 years old; 5. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Other diseases that may cause involuntary movement: drug-induced acute dystonia, tic disorders, Parkinsonism, etc. 2. suffering from the following serious diseases: history of brain trauma or cerebrovascular accident, narrow Angle glaucoma, epilepsy, myocardial infarction, unstable angina pectoris, congestive heart failure, severe liver cirrhosis, acute and chronic renal failure, severe diabetes mellitus, aplastic anemia, moderate to severe malnutrition and other serious nervous, heart, liver, kidney, endocrine, blood system and other serious physical diseases; 3. Have an intracranial mass, cerebral infarction, increased intracranial pressure, or other active central nervous system disease, including epilepsy, dementia, delirium, amnesia, or other cognitive disease; 4. Substance abuse (excluding caffeine and nicotine) in the past 3 months; 5. Those who are at high risk of suicide, or who have committed suicide or serious self-harm and need urgent intervention; 6. Refusal to sign informed consent; 7. Known to have serious adverse reactions to the study process, refused or could not cooperate to complete the study process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Pricision; Specificity;Recall;F1 score;Receiver Operating Characteristic Curve,ROC;Area Under Curve,AUC;Abnormal Involuntary Movement Scale, AIMS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tardive Dyskinesia Rating Scale, TDRS;TD Impact Scale;Rating Scale for Extrapyramidal Side Effects. RSESE;Treatment Emergent Symptom Scale;UKU Side Effects Scale; | — |
Countries
China
Contacts
The First Affiliated Hospital of the Air Force Military Medical University