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Association and Predictive Value of Blood-Derived Markers with Postoperative Complications in Elderly Patients After Major Orthopedic Surgery.

Association and Predictive Value of Blood-Derived Markers with Postoperative Complications in Elderly Patients After Major Orthopedic Surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107669
Enrollment
Unknown
Registered
2025-08-15
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative complications

Interventions

Non-postoperative complications group:None

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 60 years; 2.ASA (American Society of Anesthesiologists) classification I–IV; 3.Undergoing major orthopedic surgery (hip replacement, knee replacement, or hip fracture surgery); 4. Receiving general anesthesia or neuraxial anesthesia (e.g., spinal/epidural anesthesia).

Exclusion criteria

Exclusion criteria: 1.Pre-existing hematologic, autoimmune diseases, active infections, or advanced malignancy; 2.Severe preoperative dysfunction of the heart, lungs, kidneys, brain, or other major organs; 3.Pre-existing complications related to the outcome measures; 4.High-energy traumatic injuries (e.g., car accidents, falls from height, or crush injuries); 5.Previous radiotherapy, chemotherapy, or immunosuppressive therapy before surgery; 6.Other surgeries unrelated to postoperative complications; 7.Medical records with >20% missing data.

Design outcomes

Primary

MeasureTime frame
Blood-derived indicators;Postoperative complications;Complete blood count;Biochemical indicators;

Secondary

MeasureTime frame
Hospitalization costs;Postoperative Hospital Stay;

Countries

China

Contacts

Public ContactXiaobin Wang

Affiliated Hospital of Southwest Medical University

wangxiaobin67@163.com+86 137 0828 0087

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026