Insomnia disorder
Conditions
Interventions
Healthy Control group:None
Experimental group 1:Bilateral rTMS intervention
Experimental group 2:Right DLPFC low-frequency rTMS treatment group
Experimental group 3:Left DLPFC high-frequency rTMS treatment group
Sponsors
AnKang Hospital of traditional chinese medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with insomnia need to meet: DSM-5 diagnostic criteria for insomnia disorder; PSQI>5; age 18-65 years; Right-handed. Healthy controls need to be met: Good sleep quality in the past 3 months; PSQI<=5; age 18-65 years; Right-handed.
Exclusion criteria
Exclusion criteria: 1. Patients with insomnia do not meet the diagnostic criteria for insomnia disorder; 2. Presence of any contraindications to rTMS (e.g., history of seizures, intracranial implants); 3. Other types of sleep disorders, such as narcolepsy, parasomnia, or sleep-related movement disorders; 4. History of brain surgery or traumatic brain injury; 5. Suffering from mental or neurological diseases; 6. Being pregnant; 7. Contraindications to magnetic resonance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvements in insomnia, depressive, and anxiety symptoms of insomnia patients;Alterations in neural circuits under task-state conditions in insomnia patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of reduced activation in the sensory cortex of insomnia patients during the resting state;Changes in the level of arousal in patients with insomnia; | — |
Countries
China
Contacts
Public ContactWei Chen
AnKang Hospital of traditional chinese medicine
Outcome results
None listed