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To investigate the effect of ultrasound-guided low serratus anterior plane and rectus abdominis sheath block combined with patient-controlled intravenous analgesia on postoperative analgesia and quality of recovery in patients undergoing laparoscopic hepatectomy

To investigate the effect of ultrasound-guided low serratus anterior plane and rectus abdominis sheath block combined with patient-controlled intravenous analgesia on postoperative analgesia and quality of recovery in patients undergoing laparoscopic hepatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107619
Enrollment
Unknown
Registered
2025-08-15
Start date
2025-08-20
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Tumor

Interventions

A Group (Experimental group):SAPB was performed on the 7th and 8th intercostal spaces of the right midaxillary line after anesthesia induction
Inject 15ml of 0.25% bupivacaine liposomes into two points respectively
inject 10ml of 0.25% bupivacaine liposomes into the bilateral rectus abdominis sheaths respectively
B Group (Control group):None

Sponsors

Fudan University Affiliated Zhongshan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age range: 18 to 65 years old; 2.Body mass index (BMI) 18~30kg/m^2; 3.American Society of Anesthesiologists (ASA) classification I-II; 4.New York Heart Association (NHYA) grades I-II; 5.No obvious liver or kidney dysfunction; 6.No serious heart or lung diseases; 7.Patients and their families sign informed consent forms;

Exclusion criteria

Exclusion criteria: 1.Failed laparoscopic surgery converted to open surgery; 2.Laparoscopic hemihepatectomy and other large-scale surgeries; 3.Severe hemodynamic instability during surgery; 4.Skin infection or bleeding at the site of nerve block;5. Severe coagulation dysfunction; 6.History of allergy to local anesthetics; 7.History of abdominal surgery; 8.History of chronic pain; 9.History of drug abuse; 10.Difficult airway; 11.Serious cardiovascular diseases (chronic obstructive pulmonary disease, coronary heart disease, malignant arrhythmia); 12.Mental illness and communication disorders;

Design outcomes

Primary

MeasureTime frame
Resting Visual Analog Scale (VAS) scores within 0, 4, 12, 24, and 48 hours postoperatively;

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;The proportion of rescue analgesia in the awakening room;The time to start pressing the analgesic pump after surgery;The number of compressions of the analgesic pump within 24 hours after surgery;Cumulative morphine equivalent Meq during perioperative period;Actual extent of liver resection during surgery;QoR-15;First exhaust time after surgery;First time of getting out of bed activity after surgery;Postoperative hospitalization time;

Countries

China

Contacts

Public ContactBeibei Yu

Fudan University Affiliated Zhongshan Hospital

yubeibei521521@163.com+86 135 6414 1813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026