Pulmonary Thromboembolism(PTE)
Conditions
Interventions
Group A:Adjust the dosage of heparin or low molecular weight heparin based on anti-factor Xa level
Group B:Patients receiving heparin anticoagulation will have their heparin dosage adjusted according to activated partial thromboplastin time (APTT), while those receiving low molecular weight heparin
Sponsors
Fuwai Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.>=18 years old; 2. Patients with acute pulmonary embolism who were initially diagnosed; 3. Signed informed consent and agreed to receive heparin/low molecular weight heparin anticoagulation therapy.
Exclusion criteria
Exclusion criteria: 1. Previous history of pulmonary embolism 2. Patients cannot sign the informed consent form or cannot cooperate with the completion of the study. 3. Those who are allergic to heparin/low molecular weight heparin. 4. Previous heparin/low molecular weight heparin-induced thrombocytopenia (HIT) or heparin/low molecular weight heparin-induced of patients with a history of thrombocytopenia with thrombosis (HITT). 5. Severe bleeding disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-Pulmonary Embolism Syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of bleeding events from initial anticoagulation to 3 months of follow-up; | — |
Countries
China
Contacts
Public ContactYou Lingyan
Fuwai Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed