Benign skin lesions
Conditions
Interventions
Group of circumferential excision :Perform the surgery using the margin-based excision method, completely excising the tumor approximately 1mm outside the tumor's edge. Simulate the appearance of the
Group of fusiform excision :Design a fusiform incision that includes the tumor along the skin's relaxed tension lines, with a length-to-width ratio of approximately 2.5 to 3:1 and an angle of the fus
Sponsors
Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
2 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Male and female patients aged 1 to 40 years, clinically diagnosed with benign skin lesions such as pigmented nevi. 2. Patients who have read the informed consent form and are willing and able to undergo treatment as required by the protocol and attend follow-up appointments on time. 3. Those who agree to sign a written informed consent form; participants under the age of 18 must have a guardian sign the consent form as well. 4. The treatment area has not received any prior treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with vascular malformations or syndromes in the treatment area. 2. Patients with other apparent skin diseases in the affected area that may significantly impact the evaluation of treatment efficacy (such as contact dermatitis or purulent infections). 3. Patients with allergic constitution, keloid tendency, or those prone to scarring. 4. Patients with known severe immunodeficiency or those requiring long-term use of corticosteroids and immunosuppressants. 5. Patients with abnormal electrocardiograms or organic heart disease. 6. Patients with abnormal liver function (liver function indicators exceeding the upper limit of normal) or severe renal dysfunction (renal function indicators exceeding the upper limit of normal by 1.5 times). 7. Patients with hereditary or acquired coagulopathy, or those currently using anticoagulant medications. 8. Patients with severe neurological, psychiatric, or endocrine disorders. 9. Patients who have received treatment in the affected area before or have undergone systemic treatment for systemic diseases. 10. Pregnant or breastfeeding women, or women using inadequate contraceptive measures. 11. Individuals who participated in other clinical drug trials within the 4 weeks prior to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative incision length ;length of the scar of incision;width of the scar of incision;measurement via scar grading scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of skin lesions;The angle between the incision direction and the lowest tension line of the skin.; | — |
Countries
China
Contacts
Public ContactTian Jia
Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed