Analgesi of total knee arthroplasty
Conditions
Interventions
GNB Group(Part I):Adductor canal block combined with GNB block before operation.
IPACK Group(Part I):Adductor canal block combined with IPACK block before operation.
Control group(Part I):Adductor canal block before operation.
Diabetic SNB Group(Part II):Adductor canal block combined with SNB block before operation in diabetic patients.
Nondiabetic SNB Group(Part II):Adductor canal block combined with SNB block before operation in nondiabetic patients.
control group(Part II):Adductor canal block before operation.
Sponsors
The Third People's Hospital of Chengdu
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adult patients aged 18 to 80, classified by American College of Anesthesiologists as I to III, plan to undergo elective unilateral total knee arthroplasty under general anesthesia.
Exclusion criteria
Exclusion criteria: Contraindication to a nerve block, other connective tissue diseases affecting the knee, allergy to local anesthesia, sciatic pain, hepatic and renal insufficiency,body mass index (BMI) higher than 40 kg/m2, use of anticoagulant drugs, age 80 years, inability to comprehend or cooperate to perform this study and refusal of regional block .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The NRS pain score during movement ;The change of sciatic nerve hardness; | — |
Secondary
| Measure | Time frame |
|---|---|
| The NRS pain score during rest;Systolic pressure;Diastolic pressure;Heart rate;Recovery time of postoperative spontaneous respiration;Waking time;PACU stay time;Sufentanil consumption;AUC for pain score during the first 12 h;AUC for pain score during the first 24 h;McMaster Universities Arthritis Index (WOMAC);Oxford Knee Score (OKS);Knee Society Score (KSS);Medical Research Council (MRC) scale;Range of Motion(ROM) Test;Timed Up and Go (TUG) test ;Sufentanil consumption;The NRS pain score;McMaster Universities Arthritis Index (WOMAC);Timed Up and Go (TUG) test ; | — |
Countries
China
Contacts
Public ContactHao Jin
The Third People's Hospital of Chengdu
Outcome results
None listed