Sudden Sensorineural Hearing Loss
Conditions
Interventions
Control group (conventional treatment group):Administer oral methylprednisolone tablets and intravenous infusion of ginkgo biloba extract injection.
experimental group (vitamin D intervention group):Administer oral methylprednisolone tablets and intravenous infusion of ginkgo biloba extract injection, along with oral vitamin D3 for treatment.
Sponsors
The First People's Hospital of Yinchuan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Met the diagnostic criteria for sudden sensorineural hearing loss (SSNHL) as outlined in the Guidelines for the Diagnosis and Treatment of Sudden Hearing Loss (2015) jointly formulated by the Otorhinolaryngology Head and Neck Surgery Branch of the Chinese Medical Association and the Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery [8]; 2. No history of hearing loss caused by middle/inner ear inflammation or other etiologies; 3. No prior treatment for SSNHL before enrollment; 4. Normal hearing in the contralateral (healthy) ear; 5. No family history of hereditary deafness; 6. Serum 25-hydroxyvitamin D level <75 nmol/L (30 ng/mL); 7. Patients with stable diabetes, hypertension, or coronary heart disease were included.
Exclusion criteria
Exclusion criteria: 1. Pregnant women or patients with uncontrolled systemic comorbidities;a; family history of hereditary deafness; 3. Abnormal findings in temporal bone CT or internal auditory canal MRI (e.g., structural lesions in external/middle/inner ear); 4. Affected ear with tympanic membrane perforation, fungal infection, or ear canal malformation; 5. Non-compliance with medication regimens; 6. Renal/hepatic dysfunction or multi-system organ failure; 7. Allergy to any component of vitamin D3 capsules.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hearing improvement;Tinnitus improvement; | — |
Countries
China
Contacts
Public ContactShenxue Liang
The First People's Hospital of Yinchuan
Outcome results
None listed