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Study on Abnormal Interactive Patterns of Emotional Processing Across Stages of Depression and Their Neurophysiological Mechanisms

Study on Abnormal Interactive Patterns of Emotional Processing Across Stages of Depression and Their Neurophysiological Mechanisms

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107591
Enrollment
Unknown
Registered
2025-08-14
Start date
2025-01-07
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive disorder

Interventions

Depressive Disorder Group:No intervention
Healthy Control Group:No intervention

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for depressive disorders according to ICD-10 or DSM-5, or does not meet the diagnostic criteria for any type of mental disorder as assessed by the M.I.N.I. 2.Chinese Han nationality, men and women are not limited; 3.18-65 years old, right-handed; 4.Educational level above primary school; 5.Voluntary participation in this study.

Exclusion criteria

Exclusion criteria: 1.Conform to other diagnosis of DSM-IV axis I, such as schizophrenia, bipolar disorder; 2.Severe physical diseases with poor control, such as coronary heart disease, thyroid dysfunction; 3.He had a history of brain trauma leading to loss of consciousness, or a history of epilepsy; 4.There are visual / auditory dysfunctions that cannot be corrected to basic normal; 5.There is obvious finger movement dysfunction ( unable to click the mouse ); 6. Women in pregnancy or lactation, or persons preparing for pregnancy ( child-bearing ); 7.Received ECT / MECT treatment in the past 6 months; 8.There are contraindications to transcranial electrical stimulation; 9.Don 't agree to sign the informed consent;

Design outcomes

Primary

MeasureTime frame
Electroencephalogram testing;

Secondary

MeasureTime frame
Pro-inflammatory cytokines;Hamilton Depression Scale 17;Brain-Derived Neurotrophic Factor;

Countries

China

Contacts

Public ContactJun Wang

Wuxi Mental Health Center

woodfish2@126.com+86 510 83219310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026