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Dynamic Assessment of Ferroptosis Biomarkers and Construction of a Prognostic Prediction Model in Patients with Septic Myocardial Injury: A Prospective Cohort Study

Dynamic Assessment of Ferroptosis Biomarkers and Construction of a Prognostic Prediction Model in Patients with Septic Myocardial Injury: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107583
Enrollment
Unknown
Registered
2025-08-14
Start date
2025-08-14
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Observation group of patients with sepsis myocardial injury:None

Sponsors

Shanghai First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The diagnosis of sepsis meets the latest definition and diagnostic criteria of Sepsis 3.0; 2. There is a clear foci of infection; 3. Age>=18 years old; 4. Intensive care unit (ICU) treatment time >=24 hours. 5.Troponin T>=0.01 ng/ml within 24 hours.

Exclusion criteria

Exclusion criteria: 1. History of acute myocardial infarction, coronary heart disease, cardiomyopathy, heart valve disease, congenital heart disease, etc.; 2. Experience cardiopulmonary resuscitation, defibrillation and cardioversion; 3. Pulmonary embolism, chronic anemia, trauma, burns; 4. Combined with autoimmune system-related diseases and malignant tumors; 5. Pregnancy and lactation.

Design outcomes

Primary

MeasureTime frame
28-day prognosis;

Secondary

MeasureTime frame
90-day prognosis;Length of stay in the ICU;Total length of hospital stay;

Countries

China

Contacts

Public ContactYun Xie

Shanghai First People's Hospital

772723513@qq.com+86 152 2184 4124

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026