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Diagnostic Value of 18F-FDG PET/CT Hepatic Glucose Metabolic Imaging in Cancer-Related Cachexia and Its Impact on Survival

Diagnostic Value of 18F-FDG PET/CT Hepatic Glucose Metabolic Imaging in Cancer-Related Cachexia and Its Impact on Survival

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107580
Enrollment
Unknown
Registered
2025-08-14
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer-related cachexia

Interventions

Very high liver uptake group (HG):None
Very low liver uptake group (LG):None
Control group:None

Sponsors

China National Nuclear Corporation 416 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Healthy individuals without a history of malignant tumors, liver disease, biliary disease, or diabetes, and whose pre-FDG-injection blood glucose level is <=200 mg/dL; 2.Patients without any laboratory data within 10 days prior to the PET/CT study; 3.Cancer patients aged 18 years or older; 4.Patients who underwent 18F-FDG PET/CT scanning with complete imaging data and clinical records; 5.Patients who are able to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with liver tumors; 2.patients with blood glucose levels greater than 200 mg/dL; 3.patients younger than 18 years of age; 4.patients with extensive high metabolic lesions and reduced brain FDG uptake; 5.patients with other severe systemic diseases that may affect the study outcomes.

Design outcomes

Primary

MeasureTime frame
Hepatic FDG uptake quantified by PET/CT imaging parameters such as SUVmax and SUVmean.;Overall Survival (OS);Disease-Free Survival (DFS);

Secondary

MeasureTime frame
Laboratory nutritional and metabolic biomarkers;BMI;

Countries

China

Contacts

Public ContactYuxiao Xia

China National Nuclear Corporation 416 Hospital

hahaxiayuxiao@163.com+86 18308312313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026